Evaluation of anti-oxidant capacity of root of scutellaria baicalensis Georgi, in comparison with roots of polygonum multiflorum Thunb and Panax ginseng CA Meyer

Document Type

Journal Article

Publication Date

2010

Keywords

Chinese-medicated diet, Anti-oxidant activity, Ferric reducing/Anti-oxidant power (FRAP), Total phenol content, Scutellaria baicalensis Georgi, Polygonum multiflorum Thunb, Panax ginseng CA Meyer

DOI

10.1142/S0192415X10008263

Abstract

In Chinese communities, regular consumption of Chinese-medicated diets (CMD) (usually in the form of soup) is a traditional practice to promote health and prevent disease development. The overall improvement of health conditions is believed to be correlated with the anti-oxidant potentials of these herbs. Huangqin, roots of Scutellaria baicalensis Georgi (Lamiaceae), is one of the herbs commonly used in CMD. In this study, the anti-oxidant capacities of Huangqin extracts (water, ethanol and ether extracts) were evaluated and compared to commonly used CMD herbs, Heshouwu, roots of Polygonum multiflorum Thunb (Polygonaceae) and Renshen (or Ginseng), roots of Panax ginseng CA Meyer (Araliaceae). The anti-oxidant capacities were measured by using both cell-free assay [ferric reducing/anti-oxidant power (FRAP)] and biological methods [2,2'-azobis–(2-amidinopropane) (AAPH)-induced haemolysis assay and H2O2-induced cell damage on H9C2 cells]. Additionally, the total phenolic content was measured using Folin-Ciocalteu methods. Water extract of Huangqin has the highest anti-oxidant activities compared to the ethanol and ether extracts. A positive relationship between the anti-oxidant effects and total phenolic contents of extracts was demonstrated. This shows that Huangqin could be an effective dietary anti-oxidant that can be consumed regularly as a functional food for the prevention of oxidant/free radical-related diseases.

Source Publication

The American Journal of Chinese Medicine

Volume Number

38

Issue Number

4

First Page

815

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