Title
A phosphorescent rhenium(I) tricarbonyl polypyridine complex appended with a fructose pendant that exhibits photocytotoxicity and enhanced uptake by breast cancer cells
Document Type
Journal Article
Publication Date
2013
DOI
10.1021/om400612f
Abstract
We demonstrated that the cytotoxicity of a phosphorescent rhenium(I) polypyridine complex with a fructose pendant was enhanced upon irradiation and the cellular uptake of the complex was mediated by fructose transporters and inhibited by unmodified fructose but was independent of glucose-specific transporters. This complex has been used to image breast cancer cells, where fructose transporters are overexpressed.
Source Publication
Organometallics
Volume Number
32
Issue Number
18
ISSN
0276-7333
First Page
5098
Last Page
5102
Recommended Citation
Zhang, K.,Tso, K.,Louie, M.,Liu, H.,& Lo, K. (2013). A phosphorescent rhenium(I) tricarbonyl polypyridine complex appended with a fructose pendant that exhibits photocytotoxicity and enhanced uptake by breast cancer cells. Organometallics, 32 (18), 5098-5102. http://dx.doi.org/10.1021/om400612f