Title
An in vitro study of the antioxidant activities and effect on human DNA of the Chinese herbal decoction ‘liu wei di huang’
Document Type
Journal Article
Publication Date
2009
Keywords
Antioxidant, Comet assay, Traditional Chinese medicine, Herb, Oxidative stress
DOI
10.3109/09637480802012209
Abstract
A Chinese medicinal formulation, ‘Liu Wei Di Huang’, and its individual components have been tested for the genoprotective effect on human DNA by the comet assay. Results showed no DNA protection contributed by this prescription. However, the aqueous extracts of individual herbs, namely Cortex Moutan and Rhizoma Dioscoreae, were able to decrease by 10–15% the DNA stand break from hydrogen peroxide-mediated oxidative stress. This provides insight to further evaluate the interaction among herbs and the search for the active ingredient responsible for the DNA protective effect.
Source Publication
International Journal of Food Sciences and Nutrition
Volume Number
60
Issue Number
8
ISSN
0963-7486
First Page
662
Last Page
667
Recommended Citation
Szeto, Y.,Lei, P.,Ngai, K.,Yiu, A.,Chan, C.,Kok, E.,& Leong, C. (2009). An in vitro study of the antioxidant activities and effect on human DNA of the Chinese herbal decoction ‘liu wei di huang’. International Journal of Food Sciences and Nutrition, 60 (8), 662-667. http://dx.doi.org/10.3109/09637480802012209